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Table 2 Kinetic parameters for xanthine oxidation in HLS9 system. Constants are expressed as the mean ± SE

From: Plumbagin can potently enhance the activity of xanthine oxidase: in vitro, in vivo and in silico studies

PLB μM

Km μM

Vmax nmol/min/mg

Goodness of fit R2

CLint μL/min/mg

0

25.2 ± 2.5

0.033 ± 0.001

0.981

1.3

10

14.7 ± 1.6

0.138 ± 0.003

0.983

9.4

20

15.3 ± 1.1

0.207 ± 0.003

0.993

13.5

40

20.7 ± 3.2

0.303 ± 0.010

0.961

14.6

80

35.2 ± 4.6

0.493 ± 0.016

0.972

14.0

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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