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Table 3 Esculetin effect on myocardial tissue antioxidant enzyme’s activity in ISO induced myocardial toxicity

From: Exploring cardioprotective potential of esculetin against isoproterenol induced myocardial toxicity in rats: in vivo and in vitro evidence

 

SOD(U/mg Protein)

CATALASE (μM H202Consumed/mg Protein

GSH (μg of GSH/mg Protein)

LPO (nm of MDA/mg Protein)

Normal

9.248 ± 1.047

7.965 ± 1.217

11.65 ± 1.108

1.693 ± 0.200

Disease Control

1.646 ± 0.516#

1.159 ± 0.386#

4.027 ± 0.784#

3.313 ± 0.407#

Esculetin(10 mg/kg)

5.804 ± 0.267*

6.484 ± 1.145*

7.766 ± 0.384*

2.044 ± 0.255*

Esculetin(20 mg/kg)

7.241 ± 1.070*

9.249 ± 1.856*

9.719 ± 0.332*

1.661 ± 0.365*

  1. All values are shown as mean ± SEM and n = 6. Data analysis done by one way analysis of variance followed by the Tukey multiple comparison tests. # p < 0.05, indicate disease control compared with normal. ** p < 0.05, indicate Esculetin compared with disease control group