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Table 2 Esculetin effect on myocardial lysosomal enzyme’s activity in ISO induced myocardial toxicity

From: Exploring cardioprotective potential of esculetin against isoproterenol induced myocardial toxicity in rats: in vivo and in vitro evidence

 

β-glucuronidase (p-nitro phenol/h/mg protein)

β-glucosidase (p-nitro phenol/h/mg protein)

β-galactosidase (p-nitro phenol/h/mg protein)

Acid phosphatase (p-nitro phenol/h/mg protein)

Normal

0.425 ± 0.003

0.050 ± 0.003

0.042 ± 0.004

0.071 ± 0.008

Disease Control

0.088 ± 0.007#

0.114 ± 0.003#

0.107 ± 0.007#

0.159 ± 0.009#

Esculetin (10 mg/kg)

0.536 ± 0.005*

0.063 ± 0.005*

0.073 ± 0.005*

0.084 ± 0.005*

Esculetin (20 mg/kg)

0.42 ± 0.001*

0.06 ± 0.002*

0.062 ± 0.001*

0.079 ± 0.003*

  1. All values are shown as mean ± SEM and n = 6. Data analysis done by one way analysis of variance followed by the Tukey multiple comparison tests. # p < 0.05, indicate disease control compared with normal. * p < 0.05, indicate Esculetin compared with disease control group