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Table 1 Biochemical and hematological results in sub-acute experiment (16 injections with 8-h intervals)

From: In vitro and in vivo toxicity and antibacterial efficacy of melittin against clinical extensively drug-resistant bacteria

Groups

Urea (mg/dL)

Creatinine

(mg/dL)

AST

(U/L)

ALT

(U/L)

RBC

(106/µL)

WBC

(103/µL)

Control

44.33 ± 2.25

0.55 ± 0.05

79.00 ± 26.39

58.00 ± 21.37

9.64 ± 0.86

6.5 ± 0.23

Melittin 2.4 mg/kg

46.83 ± 2.31

0.52 ± 0.02

67.00 ± 5.36

61.00 ± 7.64

9.20 ± 0.60

5.06 ± 0.42

p-value (t-test)

0.08

0.22

0.32

0.75

0.32

0.004

  1. AST: aspartate transaminase; ALT: alanine transaminase; RBC: red blood cell; WBC: white blood cell
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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