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Fig. 4 | BMC Pharmacology and Toxicology

Fig. 4

From: In vitro and in vivo toxicity and antibacterial efficacy of melittin against clinical extensively drug-resistant bacteria

Fig. 4

The results of the survival experiment determined the efficacy of melittin, along with untreated and colistin/vancomycin controls. The neutropenic mice (n = 10 each) were inoculated with a lethal amount of A. baumannii (A-107 CFU/mouse), S. aureus (B-107 CFU/mouse), and K. pneumonia (C-108 CFU/mouse) and treated with phosphate buffered saline (PBS), melittin (2.4 mg/kg) and colistin/vancomycin as described in methods. The difference was defined as significant as *p < 0.5

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