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Table 1 Body weights and food intake of chronic DOX-induced cardiomyopathy model mice during 35 days

From: Premedication with pioglitazone prevents doxorubicin-induced left ventricular dysfunction in mice

n

Vehicle

DOX

Pio + DOX

10

20

20

Body weights (g)

 Day 0

24.9 ± 0.5

26.3 ± 0.3*

26.6 ± 0.2*

 Day 7

25.5 ± 0.5

25.4 ± 0.3

25.7 ± 0.2

 Day 14

26.1 ± 0.5

25.4 ± 0.3

25.1 ± 0.2

 Day 21

26.7 ± 0.5

24.6 ± 0.3*

24.2* ± 0.2*

 Day 28

27.1 ± 0.5

24.4 ± 0.2*

23.9* ± 0.3*

 Day 35

27.4 ± 0.5

23.9 ± 0.2*

23.4* ± 0.3*

Food intake (g/day)

 Day 0

2.6

3.1

3.4

 Day 7

2.7

2.1

2.1

 Day 14

2.8

2.5

2.4

 Day 21

2.7

2.2

2.1

 Day 28

2.6

2.2

2.0

 Day 35

2.5

2.0

1.9

  1. Data are shown as the mean ± SEs (body weights) or mean (food intake). *P < 0.05 vs. Vehicle, n Number, DOX Doxorubicin, Pio Pioglitazone
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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