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Table 3 Effect of treatment with alamandine renal oxidative stress markers in DOX-treated rats

From: Protective effect of alamandine on doxorubicin‑induced nephrotoxicity in rats

 

Sham

Control

Ala

Dox

Dox + Ala

Kidney SOD (U/g tissue)

71.90 ± 10.62

74.42 ± 9.62

69.51 ± 11.96

48.52 ± 14.93**†

59.04 ± 16.09

Kidney MDA (nmol/g tissue)

4.44 ± 1.53

4.46 ± 0.94

5.52 ± 2.61

17.3 ± 5.31**††

14.87 ± 5.36*†

Kidney GPx Activity

(u/mg protein)

11.17 ± 2.81

11.72 ± 2.09

10.26 ± 2.51

4.91 ± 2.89**†

6.61 ± 2.88

  1. Data are expressed as mean ± SD; n = 7 for each group
  2. P < 0.05, ‎†‎‎†P < 0. 01 compared to the sham‎;‎
  3. *P < 0. 05, ‎**P < 0. 01, ***P < 0.001 compared to the control