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Table 4 Cell viability (%) of ibuprofen derivatives (4a-n) at 2 μg/ml

From: New ibuprofen derivatives with thiazolidine-4-one scaffold with improved pharmaco-toxicological profile

Comp. 24 h 48 h 72 h Comp. 24 h 48 h 72 h
4a 88.47 ± 1.70 84.65 ± 1.17 78.83 ± 1.29 4 h 98.52 ± 0.88 97.98 ± 2.16 92.30 ± 1.19
4b 85.06 ± 2.01 77.07 ± 2.06 73.84 ± 1.19 4i 90.80 ± 1.89 84.62 ± 1.24 83.89 ± 2.08
4c 99.56 ± 1.46 94.88 ± 0.71 94.39 ± 1.65 4j 91.71 ± 1.95 91.07 ± 1.19 89.45 ± 1.01
4d 96.63 ± 1.77 90.17 ± 1.01 84.98 ± 0.65 4 k 89.70 ± 2.17 89.56 ± 0.15 87.85 ± 1.26
4e 89.24 ± 1.24 88.86 ± 1.53 75.31 ± 1.89 4 l 93.85 ± 1.14 92.14 ± 2.06 84.46 ± 1.59
4f 99.48 ± 0.63 98.46 ± 1.55 94.44 ± 0.10 4 m 99.64 ± 1.89 99.61 ± 1.53 95.02 ± 1.46
4 g 97.46 ± 1.52 95.75 ± 1.95 85.62 ± 0.37 4n 96.01 ± 1.14 95.00 ± 1.59 93.91 ± 1.96
Ibuprofen 98.48 ± 2.44 97.39 ± 1.30 92.64 ± 1.96 DMSO 5% 36.43 ± 1.45 14.40 ± 1.00 6.95 ± 0.38