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Fig. 3 | BMC Pharmacology and Toxicology

Fig. 3

From: Cyclosporine-a attenuates retinal inflammation by inhibiting HMGB-1 formation in rats with type 2 diabetes mellitus

Fig. 3

Retinal protein and mRNA expressions of IL-1β and TNF-α with Cs-A treatment: ELISA assay and Western Blot were performed to determine the retinal protein and mRNA expressions of IL-1β and TNF-α in the Normal, Normal +Cs-A, DM and DM + Cs-A group. (a) Protein expression of IL-1β in the retina. (b) Protein expression of TNF-α in the retina. (c) mRNA expression of IL-1β in the retina. (d) mRNA expression of TNF-α in the retina. Data are mean ± SD, **p < 0.01 vs. Normal group and Normal +Cs-A group, and ※※p < 0.01 vs. DM group. (pg/mg: pg per mg of retina)

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