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Table 1 Effect of different concentrations of flubendiamide and copper on per cent viability of rat splenocytes following their in vitro exposure to these xenobiotics

From: In vitro and in vivo effects of flubendiamide and copper on cyto-genotoxicity, oxidative stress and spleen histology of rats and its modulation by resveratrol, catechin, curcumin and α-tocopherol

Treatment

% Dead Splenocytes

Control

4.93 ± 0.67

Vehicle control (DMSO) 50 μl

7.46 ± 0.83

1.0 μM Flubendiamide

12.98 ± 1.92

2.5 μM Flubendiamide

15.13 ± 1.87

5.0 μM Flubendiamide

22.18 ± 1.67

7.5 μM Flubendiamide

24.28 ± 2.24

10 μM Flubendiamide

28.09 ± 1.33

15 μM Flubendiamide

29.76 ± 1.55

20 μM Flubendiamide

32.32 ± 1.32

40 μM Flubendiamide

45.42 ± 2.50

60 μM Flubendiamide

67.89 ± 3.14

80 μM Flubendiamide

88.81 ± 5.62

1.0 μM Copper

6.45 ± 3.04

2.5 μM Copper

10.34 ± 1.63

5.0 μM Copper

13.88 ± 1.39

7.5 μM Copper

16.66 ± 1.92

10 μM Copper

26.08 ± 4.73

15 μM Copper

28.39 ± 1.74

20 μM Copper

34.95 ± 5.87

40 μM Copper

51.09 ± 2.01

60 μM Copper

61.11 ± 2.03

80 μM Copper

76.68 ± 1.71

  1. Data presented are Mean ± SEM of three observations