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Table 4 Indole derivatives with TrmD inhibition potential in all pathogens under study

From: Prospects of Indole derivatives as methyl transfer inhibitors: antimicrobial resistance managers

Zinc Ids

Ng

− 6.7*

Ab

− 7.1*

Cc

− 7.0*

Kp

− 6.4*

Ef

− 6.5*

Hp

− 7.4*

Pa

−8.1*

Sa

− 7.7*

St

− 7.0*

ZINC04899565

−7.3

− 7.9

− 7.6

− 8.0

−6.7

− 8.4

− 10.5

− 9.5

− 7.9

ZINC49171024

−7.7

− 8.1

−9.1

− 8.0

−8.1

− 8.9

− 9.7

−10.2

− 9.0

  1. *Binding energy of native ligand