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Table 1 Baseline characteristics of the patients included in the study (n = 95)

From: Real-world efficacy and safety of eribulin in advanced and pretreated HER2-negative breast cancer in a Spanish comprehensive cancer center

Variable

N

%

Age

  < 70 years old

79

(83%)

  ≥ 70 years old

16

(17%)

Comorbidities

 Hypertension

13

(13,7%)

 Dyslipidemia

9

(9.5%)

 Diabetes Mellitus

3

(3.2%)

 Cardiorespiratory disease

9

(9.5%)

 Liver and renal disease

5

(5.3%)

 Relevant comorbidity ( grade 2)

12

(12.6%)

BMI

 BMI < 25

43

(45%)

 BMI 25–30

35

(37%)

 BMI > 30

17

(18%)

Histology

 Infiltrating ductal carcinoma

84

(88%)

 Infiltrating lobular carcinoma

11

(12%)

Tumor subtype

 ER and/or PgR positive

75

(79%)

 Triple Negative

16

(17%)

 HER2-positive

4

(4%)

Previous chemotherapies

 Taxane

93

(98%)

 Capecitabine

93

(98%)

 Vinorelbine

33

(35%)

Location of M1

 Bone

73

(77%)

 Lymph nodes

67

(71%)

 Liver

62

(65%)

 Lung

29

(31%)

 Pleura

23

(24%)

 Central nervous system

20

(21%)

 Skin

19

(20%)

Visceral metastases

 Yes

72

(76%)

 No

23

(24%)

Number of organs involved

  ≤ 2 organs

35

(37%)

  > 2 organs

60

(63%)

  1. Abbreviations: BMI body mass index, ER estrogen receptor, PgR progesterone receptor