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Table 3 Logistic Regression and Bootstrapping Model of Mortality Predictions after ADR events

From: Development of a mortality score to assess risk of adverse drug reactions among hospitalized patients with moderate to severe chronic kidney disease

 

Logistic Regression

Variable

SE

OR (95% CI)

Bootstrap SE

Bootstrap (95% BootCI)

Heart Disease

0.535

0.46 (0.16–1.32)

0.642

(0.37–2.20)

Dyslipidaemia

0.577

0.23 (0.07–0.71)

0.753

(0.42–3.44)

Electrolyte Disorder

0.661

5.72 (1.57–20.89)

0.779

(0.50–3.55)

Psychotic Agents

0.628

6.02 (1.76–20.64)

0.820

(0.41–3.65)

Creatinine Kinase ≥171 U/L

0.777

6.81 (1.49–31.20)

1.842

(0.17–4.46)

≥ 23 No. medications

0.553

4.66 (1.58–13.79)

0.923

(0.49–3.13)

Conservative management

0.547

1.59 (0.55–4.66)

0.694

(0.74–2.05)

  1. Abbreviations: BootCI, bootstrap confidence interval; CI, confidence interval; GFR, glomerular filtration rate; SE, standard error; OR, odd ratio
  2. Data are presented as odd ratios (95% confidence interval) unless otherwise stated
  3. aHeart Disease is defined as presence of vascular or/and heart failure aetiology
  4. bElectrolyte Disorder is defined as presence of hypokalaemia or hyperkalaemia
  5. cPsychrotic Agents is defined as drugs that are classified as psychotropic drugs
  6. dSI conversion: To convert Creatinine kinase to μkat/L, multiply by 58.82
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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