Fig. 1

Representative 2D and 3D images of cortical and trabecular bone tissues in mice a microscopic structure of cortical bone in control mice. b microscopic structure of cortical bone in mice receiving 40 mg/kg bw acrylamide. c microscopic structure of cortical bone in mice receiving 15% ethanol. d microscopic structure of cortical bone in mice receiving both toxins.1 non-vascular bone tissue. 2 isolated intact secondary osteons. 3 resorption lacunae. e representative reconstructed 3D image of the cortical bone in control mice. f representative reconstructed 3D image of the cortical bone in mice receiving 40 mg/kg bw acrylamide. g representative reconstructed 3D image of the cortical bone in mice receiving 15% ethanol. h representative reconstructed 3D image of the cortical bone in mice receiving both toxins. i representative reconstructed 3D image of the trabecular bone in control mice. j representative reconstructed 3D image of the trabecular bone in mice receiving 40 mg/kg bw acrylamide. k representative reconstructed 3D image of the trabecular bone in mice receiving 15% ethanol. l representative reconstructed 3D image of the trabecular bone in mice receiving both toxins