Table 5 Clinical management practices of nephrotoxicity and ototoxicity symptoms of injectables in patients on MDR-TB treatment follow-up at St.Peter’s Specialized Hospital and ALERT center, Addis Ababa, Ethiopia
Management practice & injectables involved in toxicity | Nephrotoxicity cases (N = 62) | Ototoxicity symptoms (N = 42) |
|---|---|---|
Decreased frequency of capreomycin dose to 2x/week, or 3x/week | 6 | 1 |
Withhold and discontinue capreomycin treatment | 28 | 2 |
Discontinue, and then taper capreomycin treatment | 1 | 1 |
Discontinue kanamycin treatment | Â | 1 |
Tapering capreomycin dose from 1000 to 750 mg /day +3x/week | 2 | 1 |
Stop injection for 15 days | 1 |  |
Close follow-up | 1 | Â |