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Table 8 The effect of different doses of Cypermethrin on Balb c mice which were administered orally using interagasteral tube

From: Study of the principles in the first phase of experimental pharmacology: the basic step with assumption hypothesis

Dose in mg/kg

10

50

90

Number of mice treated

1

1

1

Adverse effect within 24 hrs

❖ Distended stomach

❖ Bulging eyes

❖ Salivating

❖ Breathing difficulty

❖ Tremor

❖ Distended stomach

❖ Bulging eyes

❖ Salivating

❖ Breathing difficulty

❖ Tremor

❖ Distended stomach

❖ Bulging eyes

❖ Salivating

❖ Breathing difficulty

❖ Tremor & died after 11:36 hrs

Adverse effect within 48 hrs

❖ Slightly improved but with still breathing difficulty

❖ Died after 26:00 hrs

 

Adverse effect within 72 hrs

❖ Breathing difficulty

  

Adverse effect within 96 hrs

❖ Slightly recovered

  

Adverse effect within 120 hrs

❖ Weight loss