Study of the principles in the first phase of experimental pharmacology: the basic step with assumption hypothesis

Table 7 The effect of different doses of chlorpyrifos on Balb c mice which were administered orally using interagasteral tube

Dose in mg/kg	10	50	90
Number of mice treated	1	1	1
Adverse effect within 24 hrs	❖ Trembling ❖ Breathing difficulty ❖ Tearing, Salivating ❖ Weak	❖ Trembling ❖ Tearing, Salivating ❖ Breathing difficulty ❖ Very weak	❖ Forceful trembling ❖ Tearing, salivating ❖ Breathing difficulty ❖ Died after 12:36 hrs
Adverse effect within 48 hrs	❖ Weak ❖ Slightly recovered	❖ Breathing difficulty ❖ Very weak ❖ Trembling
Adverse effect within 72 hrs	❖ Recovered	❖ Slightly recovered
Adverse effect within 96 hrs	❖ Completely recovered	❖ Recovered
Adverse effect within 120 hrs	❖ Weight loss	❖ Weight loss

ISSN: 2050-6511