Table 4 Effects of therapeutic and supra-therapeutic doses of CGV On Serum Biochemical Parameters in Female Rats
Treatment/ mg/kg | UREA (mg/dl) | CREA (mmol/l) | CHOL (mmol/l) | TG (mol/l) | HDL (mmol/l) | LDL (mmol/l) | ALP (U/l) | ALB (U/l) | TP (U/l) |
|---|---|---|---|---|---|---|---|---|---|
Control | 9.47 ± 0.52 | 1.33 ± 0.40 | 1.31 ± 0.08 | 0.86 ± 0.06 | 0.58 ± 0.01 | 0.26 ± 0.04 | 16.18 ± 1.59 | 27.78 ± 1.60 | 9.72 ± 1.19 |
14.3 | 9.55 ± 0.42 (− 0.8) | 1.29 ± 0.21 (3.0) | 1.36 ± 0.09 (− 3.8) | 0.87 ± 0.02 (− 1.1) | 0.55 ± 0.02 (5.2) | 0.27 ± 0.04 (− 3.8) | 16.22 ± 1.78 (0.2) | 31.03 ± 1.54 (− 12.7) | 9.93 ± 1.01 (− 2.16) |
28.6 | 9.16 ± 0.55 (−0.8) | 1.13 ± 1.31 (15) | 1.32 ± 0.02 (0.8) | 0.77 ± 0.03 (10.5) | 0.58 ± 0.03 (0) | 0.28 ± 0.02 (− 7.7) | 16.30 ± 1.29 (− 0.7) | 30.44 ± 1.63 (− 9.6) | 10.46 ± 1.22 (− 7.6) |
1000 | 9.65 ± 0.32 (− 2.17) | 2.29 ± 0.27* (72.18) | 1.46 ± 0.11 (− 11.5) | 0.68 ± 0.03 (20.9) | 0.56 ± 0.01 (3.4) | 0.29 ± 0.03 (− 11.5) | 16.22 ± 2.80 (− 0.2) | 33.43 ± 2.54 (20) | 10.32 ± 1.21 () |
2000 | 9.25 ± 0.78 (2.3) | 2.13 ± 1.32* (60.2) | 1.32 ± 0.03 (− 0.8) | 0.69 ± 0.04 (19.8) | 0.59 ± 0.02 (− 1.7) | 0.27 ± 0.03 (− 3.8) | 16.30 ± 2.29 (− 0.7) | 30.25 ± 3.63 (− 8.9) | 11.36 ± 1.82 (− 6.2) |
3000 | 9.90 ± 0.21 (− 4.5) | 2.99 ± 2.07* (− 124.8) | 1.57 ± 0.09 (− 19.8) | 0.72 ± 0.03 (16.3) | 0.57 ± 0.01 (1.7) | 0.35 ± 0.03* (34.6) | 15.42 ± 1.44 (4.7) | 29.98 ± 3.02 (− 7.9) | 11.08 ± 1.25 (− 14.0) |