Subgroups | HR (95% CI) | P value | P value for interaction |
---|---|---|---|
Age | |||
  < 60–65 years | 0.92 (0.77, 1.10) | 0.38 | 0.58 |
  ≥ 60–65 years | 0.85 (0.79, 0.93) | 0.001 |  |
Gender | |||
 Male | 0.91 (0.85, 0.98) | 0.02 | 0.53 |
 Female | 0.87 (0.78, 0.98) | 0.02 |  |
Race | |||
 White | 0.94 (0.88, 1.01) | 0.09 | 0.12 |
 Black | 0.77 (0.59, 1.00) | 0.05 |  |
 Asian | 0.78 (0.62, 0.97) | 0.03 |  |
Body mass index | |||
  < 30 kg/m2 | 0.93 (0.83, 1.05) | 0.22 | 0.69 |
  ≥ 30 kg/m2 | 0.88 (0.81, 0.96) | 0.008 |  |
Glycated hemoglobin level | |||
  < 8.0–8.5% | 0.91 (0.83, 1.00) | 0.04 | 0.73 |
  ≥ 8.0–8.5% | 0.89 (0.82, 0.97) | 0.01 |  |
Insulin therapy | |||
 Yes | 0.88 (0.81, 0.97) | 0.01 | 0.98 |
 No | 0.88 (0.80, 0.98) | 0.01 |  |
Duration of diabetes | |||
  < 10–15 years | 0.91 (0.81, 1.02) | 0.09 | 0.74 |
  ≥ 10–15 years | 0.89 (0.82, 0.96) | < 0.01 |  |
History of congestive heart failure | |||
 Yes | 0.96 (0.85, 1.08) | 0.47 | 0.27 |
 No | 0.87 (0.77, 1.00) | 0.05 |  |
Estimated GFR | |||
  ≥ 60 mL/min/1.73m2 | 0.91 (0.79, 1.05) | 0.19 | 0.82 |
  < 60 mL/min/1.73m2 | 0.89 (0.72, 1.09) | 0.25 |  |
  ≥ 30 mL/min/1.73m2 | 0.88 (0.82, 0.95) | < 0.001 | 0.81 |
  < 30 mL/min/1.73m2 | 0.87 (0.55, 1.39) | 0.57 |  |