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Fig. 4 | BMC Pharmacology and Toxicology

Fig. 4

From: Anesthetic-sensitive ion channel modulation is associated with a molar water solubility cut-off

Fig. 4

Graph of GABAA receptor modulation as a function of the number of carbon atoms in a molecule (Panel a) and as a function of hydrocarbon molecular volume (Panel b). White and black bars indicate carbon numbers (Panel a) and molecular volumes (Panel b) associated with receptor potentiation and absent receptor modulation, respectively. Grey bars indicate regions for which hydrocarbon response data is not available. No pattern of consistent cut-off values associated with hydrocarbon chain length or molecular volume is evident

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