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Fig. 3 | BMC Pharmacology and Toxicology

Fig. 3

From: Anesthetic-sensitive ion channel modulation is associated with a molar water solubility cut-off

Fig. 3

GABAA receptor current potentiation (white bars) and absent whole cell current effects for eight different organic classes graphed as a function of the calculated hydrocarbon molar water solubility. The grey bars represent hydrocarbon solubility ranges within each organic class for which GABAA receptor modulation was not evaluated. Cut-off values are clustered between 6.0 × 10− 5 and 2.5 × 10− 4 M

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