Fig. 4
Individual pharmacokinetic ratios of randomly-selected generic products to the reference product of 14 immediate-release, non-combinational, oral drugs. Each reference product (R) was compared to 3 generic products (Ga, Gb, Gc). Data represent percentage of individual generic/reference ratios that are <0.75 (closed bars) or >1.25 (open bars). a Evaluation of time of maximum concentration (Tmax). b Evaluation of area-under-the-concentration-time curve to time of maximum concentration of reference product, calculated for each subject (AUCReftmax)