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Fig. 4 | BMC Pharmacology and Toxicology

Fig. 4

From: Haloperidol affects bones while clozapine alters metabolic parameters - sex specific effects in rats perinatally treated with phencyclidine

Fig. 4

Comparative review of proximal femoral metaphysis in female rats (haematoxylin and eosin; original magnification ×40; arrows point to trabecular area). Histology of the femur in: a) control animals (NaCl); b) animals perinatally treated with phencyclidine (PCP) showing a significant reduction of trabecular area; c) animals perinatally treated with NaCl followed by treatment with haloperidol (NaCl-H); d) animals perinatally treated with PCP followed by treatment with haloperidol (PCP-H) showing a significant decrease of trabecular area compared to NaCl animals and a significant increase of trabecular area compared to PCP animals; e) animals perinatally treated with NaCl followed by treatment with clozapine (NaCl-C); f) animals perinatally treated with PCP followed by treatment with clozapine (PCP-C) showing a significant increase of trabecular area compared to both NaCl and PCP animals

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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