Table 1 Intra- and inter-day accuracy and precision of FMS assay for various matrices
From: Placental transfer and mammary excretion of a novel angiotensin receptor blocker fimasartan in rats
Matrix | Concentration (ng/mL) | |||||
|---|---|---|---|---|---|---|
450 | 90 | 2 | 0.5 | |||
Plasma | Intra-day (n = 4) | Accuracy (%) | 96.6 | 98.8 | 99.6 | 112.2 |
Precision (CV %) | 1.0 | 0.4 | 2.4 | 8.0 | ||
Inter-day (n = 3) | Accuracy (%) | 100.7 | 99.6 | 94.2 | 117.9 | |
Precision (CV %) | 7.6 | 3.5 | 3.8 | 3.8 | ||
Placenta | Intra-day (n = 4) | Accuracy (%) | 104.4 | 94.4 | 89.9 | 111.0 |
Precision (CV %) | 1.5 | 0.8 | 3.7 | 6.4 | ||
Inter-day (n = 3) | Accuracy (%) | 97.9 | 95.3 | 89.2 | 102.7 | |
Precision (CV %) | 4.4 | 4.1 | 2.3 | 12.3 | ||
Amniotic Fluid | Intra-day (n = 4) | Accuracy (%) | 102.3 | 100.0 | 97.0 | 114.8 |
Precision (CV %) | 0.4 | 0.7 | 2.9 | 2.5 | ||
Inter-day (n = 3) | Accuracy (%) | 99.6 | 95.4 | 87.7 | 116.9 | |
Precision (CV %) | 2.1 | 3.8 | 2.0 | 1.2 | ||
Fetus | Intra-day (n = 4) | Accuracy (%) | 98.7 | 96.1 | 89.0 | 98.5 |
Precision (%) | 1.4 | 1.4 | 2.3 | 10.1 | ||
Inter-day (n = 3) | Accuracy (%) | 94.9 | 93.0 | 97.0 | 110.7 | |
Precision (CV %) | 0.9 | 0.7 | 7.8 | 10.4 | ||
Milk | Intra-day (n = 4) | Accuracy (%) | 97.3 | 94.7 | 92.4 | 109.5 |
Precision (CV %) | 1.6 | 1.2 | 5.3 | 5.3 | ||
Inter-day (n = 3) | Accuracy (%) | 102.7 | 98.6 | 88.8 | 94.1 | |
Precision (CV %) | 3.0 | 3.5 | 2.3 | 8.5 | ||