Fig. 2
From: Placental transfer and mammary excretion of a novel angiotensin receptor blocker fimasartan in rats
Fimasartan concentrations in a plasma and b milk in lactating rats after i.v. injection (2.7 and 5.5 mg/kg) followed by i.v. infusion (0.17 and 0.34 mg/h/kg) of fimasartan for target Css, plasma of 100 (n = 7) and 200 ng/mL (n = 5), respectively. Bold (target Css, plasma =100 ng/mL) and dashed (target Css, plasma =200 ng/mL) lines represent 10 and 90 % prediction intervals. Data are presented as the mean ± S.D. *: p < 0.05, 100 vs. 200 ng/mL