Figure 1.From: Evaluating a possible role for PKG1α redox state in chronic hypoxia-induced pulmonary hypertensionDifferential responses of WT or Cys42Ser PKGIα KI tissues to acute or chronic hypoxia (a) Decrease in PKG1α disulfide levels in mouse pulmonary artery under acute hypoxia. (b) PKG1α disulfide formation in mouse lung and (c) right ventricle after chronic hypoxia. (d) Fulton index, (e) Right ventricle systolic pressure and (f) pulmonary flow velocity in KI mice compared with WT mice after HPAH. *p≤0.05, **p≤0.01, ***p≤0.001, by t-test. n=8-10/group.Back to article page