Table 1 Baseline patient demographics and clinical characteristics
Palonosetron | Ondansetron | Total | |
|---|---|---|---|
(n = 48) | (n = 50) | (N = 98) | |
Age (y) | |||
Mean (SD) | 41 (10.2) | 43 (13.8) | 42 (12.1) |
Min, max | 22, 62 | 21, 83 | 21, 83 |
Sex | |||
Female, n (%) | 48 (100.0) | 50 (100.0) | 98 (100.0) |
Race, n (%) | |||
White | 36 (75.0) | 36 (72.0) | 72 (73.5) |
Black or African American | 7 (14.6) | 9 (18.0) | 16 (16.3) |
Asian | 1 (2.1) | 3 (6.0) | 4 (4.1) |
Other | 4 (8.3) | 2 (4.0) | 6 (6.1) |
Nonsmoker*, n (%) | 45 (93.8) | 49 (98.0) | 94 (95.9) |
BMI (kg/m2) | |||
Mean (SD) | 27.2 (5.4) | 27.8 (5.0) | 27.5 (5.2) |
Min, max | 17, 38 | 20, 39 | 17, 39 |
Duration of laparoscopic surgery (min) | |||
Mean (SD) | 113.3 (69.4) | 102.0 (59.8) | 107.6 (64.6) |
Median | 92.5 | 81.5 | 88.5 |
Min, max | 26, 306 | 34, 282 | 26, 306 |
Baseline NRS for nausea severity | |||
n | 47 | 48 | 95 |
Mean (SD) | 5.7 (1.84) | 5.9 (1.86) | 5.8 (1.84) |
Min, max | 2, 10 | 3, 10 | 2, 10 |
History of PONV†, n (%) | 30 (62.5) | 27 (54.0) | 57 (58.2) |
Type of laparoscopic surgery, n (%) | |||
Gynecological | 37 (77.1) | 31 (62.0) | 68 (69.4) |
Abdominal | 11 (22.9) | 19 (38.0) | 30 (30.6) |
ASA classification, n (%) | |||
I | 20 (41.7) | 20 (40.0) | 40 (40.8) |
II | 25 (52.1) | 24 (48.0) | 49 (50.0) |
III | 3 (6.3) | 6 (12.0) | 9 (9.2) |
Baseline opioid use, n (%) | 47 (97.9) | 50 (100.0) | 97 (99.0) |