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Figure 2 | BMC Pharmacology and Toxicology

Figure 2

From: Melatonin analgesia is associated with improvement of the descending endogenous pain-modulating system in fibromyalgia: a phase II, randomized, double-dummy, controlled trial

Figure 2

Mean pain levels as Delta value (scores on VAS (0-100 mm) in last week of treatment minus scores one week pretreatment) in the three experimental groups. The error bars indicate the standard error of the mean. A letter b indicates a significant difference between the melatonin group and melatonin + amitriptyline groups compared with the amitriptyline group (P < 0.05). All comparisons were performed using a mixed analysis of variance (ANOVA) model, followed by the Bonferroni correction for post hoc multiple comparisons.

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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