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Table 1 General characteristics of patients

From: Pharmacokinetics of piperacillin/tazobactam in cancer patients with hematological malignancies and febrile neutropenia after chemotherapy

Parameter

Number (%)

Age (years)

 

 18– 24

7 (50.0)

 25 - 31

3 (21,4)

 40 - 60

4 (28.6)

Sex

 

 Female

8 (57.1)

 Male

6 (42.9)

Weight (kg)

 

 40 - 50

5 (35.7)

 51 – 60

6 (42.9)

 61 - 80

3 (21.4)

 Mean ± SD = 56.4 ± 11.2

 

Height (cm)

 

 150 – 160

9 (64.3)

 161 – 170

4 (28.6)

 171 – 180

1 ( 7.1)

BMI kg/m 2

 

 17.0 – 22.0

8 (57.2)

 22.1 – 27.0

5 (35.7)

 27.1 – 32.0

1 (7.1)

 Mean ± SD = 21.9 ± 4.0

 

Creatinine clearance (mg/mL)

 

 80 - 110

3 (21.4)

 111 - 140

6 (42.9)

 141 - 170

5 (35.7)

Albumin g/dL

 

 2.0 – 2.6

3 (21.4)

 2.7 – 3.3

7 (50.0)

 3.4 – 4.0

4 (28.6)

 Mean ± SD = 3.0 ± 0.6

 

Antibiotic given in the previous month?

 

 Yes

5 (35.7)

 No

9 (64.3)

Malignancy

 

 Lymphoma

2 (14.3)

 Lymphoid leukemia

9 (64.3)

 Myeloid leukemia

3 (21.4)

Number of neutrophils/mm 3

 

 Range

0–2380

 Mean ± SD

208(603.2)

Therapy cycles

 

 1 – 2

6 (42.9)

 3 – 5

3(21.4)

 6 - 8

5 (35.7)

FN-associated chemotherapy

 

 Hyper-CVAD

10 (71.4)

 No Hyper-CVAD

4 (28.6)

  1. BMI, body mass index; FN, febrile neutropenia; GFR, glomerular filtration rate.
  2. For Hyper-CVAD chemotherapy, course A comprised cyclophosphamide, vincristine, doxorubicin and dexamethasone, and course B consisted of methotrexate and cytarabine.
  3. Mentioned on page 6.