Table 3 Performance of the CASA (LBM_PE1) and previously published FFM prediction equations in the NWAHS and FAMAS cohorts (age 50 years and over) across various age groupings

Age 50–64, years (n = 1265)

LBM _DXA

52.27 (11.2)

Heitmann equation

56.47 (10.8)

4.20 (3.99, 4.40)

<0.001

0.944*

0.879 (0.868, 0.890) [0.932]

-11.6, 3.23

5.60 (5.26, 5.95)

Janmahasatian equation

55.62 (11.2)

3.35 (3.15, 3.55)

<0.001

0.948*

0.907 (0.897, 0.915) [0.956]

-10.6, 3.85

4.92 (4.61, 5.23)

Deurenberg equation

53.15 (10.0)

0.87 (0.66, 1.09)

<0.001

0.938*

0.929 (0.921, 0.936) [0.990]

-8.72, 6.98

4.02 (3.73, 4.31)

LBM _PE1

52.77 (10.7)

0.50 (0.30, 0.70)

<0.001

0.948*

0.946 (0.939, 0.951) [0.998]

-6.68, 7.68

3.62 (3.36, 3.88)

Age 65–79, years (n = 882)

LBM _DXA

49.09 (9.91)

Heitmann equation

52.23 (10.0)

3.14 (2.90, 3.38)

<0.001

0.933*

0.887 (0.873, 0.899) [0.951]

-10.5, 4.18

4.82 (4.35, 5.29)

Janmahasatian equation

53.03 (10.5)

3.93 (3.69, 4.18)

<0.001

0.933*

0.862 (0.846, 0.876) [0.925]

-11.5, 3.66

5.46 (4.97, 5.95)

Deurenberg equation

48.19 (9.14)

-0.90 (-1.15, -0.65)

<0.001

0.924*

0.916 (0.905, 0.926) [0.993]

-6.70, 8.50

3.90 (3.45, 4.35)

LBM _PE1

50.20 (10.2)

0.98 (0.73, 1.22)

<0.001

0.929*

0.925 (0.915, 0.934) [0.995]

-6.57, 8.53

3.90 (3.48, 4.32)

Age ≥80, years (n = 140)

LBM _DXA

44.48 (8.64)

Heitmann equation

46.71 (9.20)

2.23 (1.60, 2.85)

<0.001

0.929*

0.902 (0.868, 0.928) [0.969]

-9.05, 4.59

4.06 (3.20, 4.92)

Janmahasatian equation

48.46 (10.1)

3.97 (3.29, 4.66)

<0.001

0.936*

0.850 (0.806, 0.883) [0.906]

-11.4, 3.46

5.43 (4.31, 6.55)

Deurenberg equation

42.46 (8.41)

-2.03 (-2.58, -1.48)

<0.001

0.937*

0.911 (0.880, 0.934) [0.971]

-3.97, 8.03

3.61 (2.85, 4.37)

LBM _PE1

45.84 (9.81)

1.36 (0.80, 1.93)

<0.001

0.941*

0.923 (0.897, 0.943) [0.981]

-5.39, 8.11

3.63 (2.90, 4.36)