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Figure 1 | BMC Pharmacology and Toxicology

Figure 1

From: Treatment with CNX-011-67, a novel GPR40 agonist, delays onset and progression of diabetes and improves beta cell preservation and function in male ZDF rats

Figure 1

Effects of CNX-011-67 on body weight, fed consumption, fasting and fed glucose and insulin levels. Fasting (A) and fed (B) Glucose levels were monitored weekly. (Black circle)-Lean, (Black Diamond)-Vehicle control, (Black Triangle)-CNX-011-67 (5 mg/kg). Similarly, fasting (C) and fed (D) insulin levels were monitored weekly. (Black Diamond)-Vehicle control, (Black Triangle)-CNX-011-67 (5 mg/kg) Data in all panels are mean ± SEM (n = 10/group). (E) & (F) Body weight and feed consumption were monitored weekly. Statistical comparison between control and treatment group was conducted by One-way ANOVA followed by Dunnett’s post test correction for glucose while unpaired Student’s t test was performed for insulin levels. (*p < 0.05, **p < 0.01 and ***p < 0.001).

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